All about Peyronie's disease

All about Peyronie's disease

Peyronie's disease (PD) is an acquired connective tissue disorder of the tunica albuginea of the corpus cavernosum, characterized by excessive fibrosis and plaque formation. PD can result in significant physical and psychological morbidity; as it may prevent intercourse and cause adverse impacts on partner relationships. The exact etiology and pathophysiology remain unclear, and many misconcept...

Treatment of Peyronies Disease (pd) by Extracorporeal Shock Waves (esw)

All About

We explore the C2-equivariant spectra Tmf1(3) and TMF1(3). In particular, we compute their C2-equivariant Picard groups and the C2-equivariant Anderson dual of Tmf1(3). This implies corresponding results for the fixed point spectra TMF0(3) and Tmf0(3). Furthermore, we prove a Real Landweber exact functor theorem.

Microglia in Alzheimer's Disease: It's All About Context

Neuroinflammation is now regarded as both an early event and prime mover in the pathobiology of Alzheimer disease (AD), a neurodegenerative disease that represents a growing public health threat. As the resident innate immune cells within the central nervous system, microglia are centrally positioned as key orchestrators of brain inflammation. It is now accepted that numerous forms of activated...

It’s Not Necessarily All about the Delivery in Huntington’s Disease

Existing models of Huntington's disease posit that deficits in BDNF delivery to the striatum contribute to atrophy and motor impairment. In this issue of Neuron, Plotkin et al. (2014) show that BDNF delivery is normal but downstream signaling via TrkB and p75 is impaired, leading to corticostriatal synaptic dysfunction.